ITSP Solutions µSPE Cleans up Samples in a Variety of Industries
Consider ITSP as a Wellness Program for your Analytical Instrument
ITSP Solutions, Inc. provides your lab with a modern solid phase extraction (SPE) device that incorporates µSPE into the autosampler of the LC-MS-MS and now your GC-MS-MS. ITSP’s µSPE solution replaces the tedious manual off-line process of sample clean-up long considered the gold-standard of sample preparation without slowing down the analytical instrument.
News
USPTO Issues Official Trademark Registration for SmartSPE®
On December 24, 2024 the United States Patent and Trademark Office (USPTO) issued U.S. Application Serial No. 98258650 Trademark Registration Number 7619250 for SmartSPE. The
Alternative Bed Mass and/or Septa Configurations
Two common questions that arise from ITSP VARs, OEMs and Customers revolves around alternative bed masses and septa. BED MASS ALTERNATIVES: Sorbent bed mass can
ITSP® SmartSPE® Compatible Syringes
ITSP Solutions has assembled a selection of syringes to properly pierce ITSP’s septa. It has long been known that piercing an autosampler vial’s septum required
Product Overview


ITSP’s µSPE solution incorporates SmartSPE® technology.
The unique shape of ITSP Solutions’ µSPE cartridge lets the popular CTC Analytics PAL3 RTC to use the analytical syringes’ precision-flow capability to accurately pass solvents and sample through the cartridge. Because of this break-through combination of technologies we are calling this SmartSPE®.

ITSP’s µSPE cartridge is available for GC-MS-MS
The PAL3 RTC has a new tool that allows GC-MS-MS instruments to prepare samples using the syringe tool changer to off three different syringes.

SmartSPE® Uses Look-Ahead for Simultaneous Prep and Analysis
The analytical instruments’ software that controls both the analytical instrument and the PAL3 RTC sample handler has a feature called Look-Ahead. This feature allows the RTC sample handler to prep a sample while the prior sample is being measured and the prepped to receive the next cleaned-up sample.

SmartSPE® allows Enrichment without Dry-Downs
Use of chromatographic SPE knowledge. Cation exchange of basic drugs in blood (always mixed mode, 50 μm particles)

Automation Enabled via SPE Cartridge Transport on Syringe Needle
No limits; all sorbents supported. Accurate 50 to 100 ul elution with ease. On/offline automation with PAL System sample handler.

SmartSPE® is Chromatography!
Optimized outcomes require accurate flow. SPE flow-driven pneumatically or by vacuum can not achieve and maintain optimum flow.