Agilent Plexa PCX sorbent uses a polymeric cation exchange resin that combines the outstanding properties of Bond Elut Plexa – superior flow characteristics and improved analytical performance – with strong cation exchange functionalities. This mixed-mode RP/SCX (Reverse Phase & Strong Cation eXchange) SPE sorbent removes neutral and acidic interference compounds from sample matrices and concentrates basic analytes – thereby improving sensitivity in the determination of basic compounds. It is used in clinical and forensic sample cleanup methods, e.g. to extract opiates from patient urine samples in pain management analytical laboratories for LC/MSMS analysis.
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