ITSP QuEChERS Cleanup released at Pittcon 2014

Hill Laboratories (New Zealand) presented a poster at Pittcon 2014 illustrating the advantages of ITSP over dispersive SPE (dSPE) for the cleanup of QuEChERS extracts. ITSP QuEChERS cleanup eliminates the need for matrix-matched calibration standards for both GC and LC pesticide residue analyses of QuEChERS extracts. QuEChERS methods commonly use matrix-matched calibration standards to overcome suppression or enhancement of instrument signals by sample matrices. Non-polar matrices (oils) can be problematic for LC-MS/MS analyses of more difficult sample types such as spices or food ingredients. ITSP QuEChERS cleanup eliminates the need for matrix-matched calibration standards for both GC and LC pesticide residue analyses of QuEChERS extracts. ITSP removes more non-polar matrix than dSPE and gives improved recoveries compared to dSPE. Effective matrix removal by ITSP allows the use of solvent-only LC-MS/MS calibration standards with acceptable recoveries of most pesticides in the large suite (422 analyte peaks) described in the poster.